The Command Post has a comprehensive list of ways to contribute to relief efforts in the aftermath of Sunday's earthquake. Personally, I think you can't go wrong with Medecins Sans Frontieres, Oxfam and Red Cross / Red Crescent.
Sorry if this post seems terse and uninteresting, but the alternative was some wank about Voltaire and the Lisbon Disaster of 1755, so direct your gratitude at being spared that to the organisations listed above.